BC Centre for Excellence in HIV/AIDS CDET Committee Statement on the use of COVID-19 mRNA vaccines (Pfizer and Moderna) in Persons living with HIV


The BC-CfE’s Committee for Drug Evaluation and Therapy has evaluated the use of Pfizer and Moderna’s COVID-19 mRNA vaccines for Persons Living With HIV. It is the opinion of the CDET that People living with HIV (PWLH) aged 18 years or older may be vaccinated for Covid-19 if they meet current public health criteria for priority groups and if they have no contraindications. These are not live-virus vaccines and are not expected to be associated with more serious adverse events among immunocompromised individuals.

People Living With HIV on HAART with undetectable pVL and CD4 counts above 200/mm3 are likely to be at no additional risk if vaccinated with the Pfizer or Moderna vaccines. However, risks associated with these vaccines are less clear among those with detectable pVL or low CD4 counts below 200/mm3. This uncertainty is because immunocompromised subjects were not included in these vaccine studies.

Download: BC Centre for Excellence in HIV/AIDS CDET Committee Statement

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